Answer: C.
Option A is incorrect since Route 53 latency routing only calculates latency between different endpoints based on the Internet traffic & location proximity rather than optimizing the network for fast data transfers.
Option B is incorrect since Direct Connect is used for very specific purposes like extreme security requirements for the data transfer.
Also, establishing multiple Direct Connect infrastructures would be expensive from a cost standpoint.
Option C is CORRECT.
The best way to address this scenario is to route the requests to the nearest CloudFront edge location from the different Geographic locations.
Edge locations provide a fast network infrastructure bypassing much of the internet for delivering content to S3 destinations.
Performance gains of nearly 50 - 500% can be observed while using S3 Transfer Acceleration.
Option D is incorrect.
It is possible to use S3 endpoints directly for data transfer.