Memory management in Blowfish Cipher implementation is crucial. The cipher uses a large amount of memory due to its 18-entry P-array and four S-boxes, each with 256 entries. To manage this, you can use dynamic memory allocation techniques like malloc() or calloc() in C/C++ to allocate the required space at runtime. This allows for efficient utilization of memory as it’s allocated only when needed and freed after use using free(). It also helps avoid memory leaks which could degrade performance over time. For languages that handle garbage collection automatically like Java, ensure your objects are eligible for garbage collection once they’re no longer needed by nullifying references.