Visual block mode in Vim is useful when editing columns of text or code. For instance, if you have a list of variables that need to be initialized with the same value, instead of manually typing it for each variable, visual block mode can be used. You would enter this mode by pressing ‘Ctrl + v’, then select the lines where the initialization should occur and type the desired value once. This will apply the change across all selected lines simultaneously, saving time and reducing potential errors.